Showing posts with label I. Show all posts
Showing posts with label I. Show all posts

Ivermectin

Generic Name : Ivermectin

TradeName :
IVERMECTOL, Stromectol

Overview : Ivermectin used in treatment of infections caused by parasites. It is an anthelmintic which works by killing sensitive parasites.

Why it is prescribed (Indications) : It binds selectively to glutamate gated chloride ion channels which occur in invertebrate nerve muscle cells which leads to increase in permeability of cell membrane to chloride ions with hyperpolarization of nerve or muscle cell, resulting in paralysis and death of parasite.

When it is not to be taken (Contraindications) : Before taking ivermectin, consult your doctor about any medical conditions that you have. If you are suffering from liver problems, avoid using ivermectin. Inform your doctor if you are pregnant or plan to become pregnant during treatment.

When it is to be taken : It is administered as a single oral dose therapy. Scabies & strongyloidiasis. 200mg/kg/bw onchocerciasis - 150mg/kg bw.

Missed a Dose? :
Ivermectin is usually given as a single dose, which you will probably not miss. In case you are taking a repeat dose of ivermectin , consult your doctor for specific instructions.

How it should be taken
: The medication comes in the form of 3 & 6mg tablets which usually taken in single dose on an empty stomach with a full glass of water.

Special Instruction :
Ivermectin can cause lightheadedness. Be care ful while driving, use machines, or do anything else that could be dangerous if you are lightheaded . If these reactions occur, immediately consult with your doctor.

Side Effects :
Get medical help if you have any of these signs of an allergic reactions, difficulty breathing; swelling of your face, lips, tongue, or throat. Change in vision or problems with your vision; eye redness, swelling, or pain; or seizure.

Other Precautions :
Patients taking Ivermectin have developed a serious and sometimes fatal brain problem. Inform your doctor at once if you have symptoms such as unusual back pain, eye bleeding, shortness of breath, failure to control bladder or bowel, trouble walking or standing, mental changes unusual weakness, or seizures.

Drug Interactions :
Many drugs can affect ivermectin. Inform your doctor about all the medications and over-the-counter medications you take which includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not take new medication without informing your doctor.

Storage Conditions :
Store at room temperature.

IXABEPILONE

Generic Name : IXABEPILONE

TradeName
: Ixempra®

Why it is prescribed (Indications) : This medication is prescribed for breast cancer either alone or in combination with capecitabine. It is a microtubule inhibitor. It kills cancer cells.

When it is not to be taken (Contraindications) : Liver disease, caution need during Pregnancy and lactation.

When it is to be taken : Adults IV 40 mg/m 2 over 3 h every 3 wk. Patients with body surface area more than 2.2 m 2 should be calculated based on 2.2 m 2 .

How it should be taken : This medication available in the form of injection to be injected intravenously (into a vein) by healthcare provider. It is usually given once every 3 weeks.

Special Instruction :
*Do not eat grapefruit or drink grapefruit juice while using this medication.*It may cause drowsiness or dizziness. Do not drive a car or operate machinery while taking this medication.*Monitor complete blood counts and liver function, may be performed while taking this medication. *Caution need for patients with history of diabetes; any condition that causes numbness, burning or tingling in your hands or feet; or heart disease.

Side Effects :
CENTRAL NERVOUS SYSTEM:
Confusion, difficulty in sleeping, dizziness, headache.
GI
Vomiting, diarrhea, stomach pain
SKIN
Hair loss, numbness or burning, hives, rash.
MISCELLANEOUS:
Weight loss, watery eyes, difficulty tasting food, tiredness, faintness, chills, cough, sudden swelling, chest pain.

Other Precautions :
While taking this medication, use effective contraceptives to avoid pregnancy.

Storage Conditions :

Normally handled and stored by healthcare providers.

Itraconazole

Generic Name : Itraconazole

TradeName : CANDITRAL, ITASPOR, SPORANOX

Why it is prescribed (Indications) : It is an antifungal drug and is meant for oral use. It is very effective in a wide range of superficail and deep seated fungal infections.

When it is to be taken
: Dermatophytoses, Tinea versicolor, onychomycoses, oropharyngeal candidiasis, vulvovaginal candidiasis, cutaneous candidiasis, chronic mucocutaneous candidiasis, oculomycoses, systemic mycoses, subcutaneous mycoses. It is also used in prophylaxis against opportunistic mycoses in HIV infected patients and those on immunosuppresant therapy.

How it should be taken : Dosage: Alternative in systemic infections: 200 mg once daily increased in invasive or disseminated disease and in cryptococcal meningitis to 200mg twice daily.

Special Instruction :

Hypersensitivity, Co-administration of Terfenadine or Astemizole with Itraconazole is contraindicated.

Side Effects :
Nausea,vomiting, skin rash, dizziness, depression, paraesthesias,vertigo, pedal oedema and loss of libido.

Other Precautions :

Hepatic impairment.Safety and efficacy in children has not been established. Pregnancy: Contraindicated. Lactation: Contraindicated. Elders: Not recommended.

Storage Conditions :
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Isotretinoin

Generic Name : Isotretinoin

TradeName : Etretinate, Tretinoin.

Why it is prescribed
(Indications) : Isotretinoin is used to treat severe acne that has not responded to oral or topical anti-infectives. It also has been used for other skin dosorders, including psoriasis.

When it is to be taken
: Isotretinoin is usually taken twice a day. Follow the instructions on your prescription label carefully. You may not notice any improvement in your condition until after four to six weeks of treatment, and your acne may actually get worse during the first few weeks.

How it should be taken : Isotretinoin comes in the form of capsules. You prescription labels tells you how much to take at each dose.

Special Instruction :

1. Because isotretinoin is similar to vitamin A, do not take any vitamin supplements that contain vitamin A to avoid possible toxic reactions.
2. Keep all appointments with your doctor and the laboratory. Your dose may be adjusted frequently, depending on your response to the drug, and you may have blood test periodically.
3. Isotretinoin can increase the amount of fat in your blood. Limit your intake of dietary fat and alcoholic beverages while taking isotretinoin.
4. Take the missed dose as soon as you remember it. However, if you remember a missed dose near the time you are scheduled to take the next dose, take only the scheduled dose. Do not take a double dose.

Side Effects :

1. Red, cracked, and sore lips; red, itchy, dry, and inflamed eyes; dry mouth and nose; thinning of the hair; headache; fatigue; nausea. Contact your doctor if these effects are severe.
2. Bone or joint pains, muscle aches, skin peeling, skin infections, vision problems. Contact your doctor.

Other Precautions :
1. Isotretinoin has been reported to cause serious harm to unborn babies when taken during pregnancy. Women who are pregant, who intend to become pregnant, or who are breast-feeding should tell ther doctors before taking this medication.
2. If you think you may be pregnant , stop taking isotretinoin and have a pregnancy test. Use a reliable method of birth control for one month before taking, while taking, and for one month afer discontining this drug.
3. Tell your doctor if you have diabetes, a high amount of fat in your blood, or a family history of high triglycerides in the blod.
4. Do not donate blood while you take isotretinoin and for at least one month after you stop taking it.
5. Limit your exposure to sunlight and sunlamps. Use a sunscreen product and wear protective clothing when you are exposed to direct sunlight.
6. Isotretinoin can affect your night vision. Be cautious when driving or operating any machinery after dark.
7. If you wear contact lenses
, you may not tolerate them while you take isotretinoin.
8. Do not allow anyone else to take this medication.

Storage Conditions :
Keep this medication in the container it came in, tightly closed, and out of the reach of children. Store it away from light.

Isosorbide

Generic Name : Isosorbide

TradeName
: Cardicap, Ditrate, Isordil, Isordil Sublingual, Sorbitrate

Why it is prescribed (Indications) : Isosorbide affects the supply of blood and oxygen to the heart, thereby preventing and relieving chest pain i.e., angina pectoris.

When it is to be taken :
1. Isosorbide comes in the form of regular, sublingual, chewable, and extended-release tablets and in extended-release capsules. Follow the instructions on your prescription label carefully.
2. Isosorbide chewable and sublingual tablets are used to relieve chest pain during attacks and to prevent pain before activities known to provoke attacks e.g., climbing stairs, sexual activity, walking uphill, and being outside in cold weather. If needed to prevent attacks, the dose may be repeated every two or three hours. Carry the tablets with you at all times.
3. When an attck occurs, sit down. Chew a chewable tablet thoroughly and swallow it, or place a sublingual tablet under your tongue or between your cheek and gum and allow it to dissolve. Do not swallow sublingual tablets. Try not to slwallow saliva too often until they dissolve.
4. The drug starts to work within three minutes. If pain is not relieved within five or 10 minutes, take another dose. Call for assistance or go to a hospital emergency department if pain persists after you have taken three doses and 15 to 30 minutes have passed.
5. Isosorbide regular tablets and extended-release tablets and capsules are to be swallowed and not chewed or dissolved in your mouth on a regular schedule to prevent angina. They are not used to relieve chest pain during an attack because they take too long to take effect.
6. Regular tablets usualy are taken three or four times a day on an empty stomach or at least one hour before or two hours after meals.
7. Extended-release tablets and capsules usually are taken every 6,8 or 12 hours.

How it should be taken :

1. Isosorbide comes in the form of regular, sublingual, chewable, and extended-release tablets and in extended-release capsules. Follow the instructions on your prescription label carefully.
2. Isosorbide chewable and sublingual tablets are u

Special Instruction :

1. If you take isosorbide on a regular schedule to prevent angina but you continue to have attacks, contact your doctor.
2. Do not stop taking it without consulting your doctor. Stopping the drug abruptly can cause chest pain. Your doctor probably will want to decrease your dose gradually.
3. Keep all appointments with your doctor and report any chest pain that you experience.
4. Isosorbide can lose its effectiveness over time. Contact your doctor if you no longer get relief from your prescribed dose.
5. Follow your doctor's instructions to stop smoking, lose weight, rest, and avoid situations that cause angina.
6. If you take isosorbide on a regular schedule, take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals.

Side Effects :

1. Headache. If you take isosorbide on a reguar schdeule, take it with meals. If headaches persist, ask your doctor if you may take aspirin or acetaminophen. Do not take any medication for headache or change your dose without consulting your doctor.
2. Dizziness, lightheadedness, weakness, faintness, and fast heartbeat, especially while standing or when in a warm place. Lie or sit down. Contact your doctor if these effects persist or if you faint.
3. Stomach upset. Contact your doctor if this problem is severe or persists. 4. Blurred vision, dry mouth, skin rash. Contact your doctor immediately.

Other Precautions :
1. Before you take isosorbide, tell your doctor if you have intestinal disease or if you ever had a bad reaction to amyl nitrite, erythrityl tetranitrate, nitroglycerin, or pentaerythritol tetranitrate.
2. Before you use isosorbide, tell your doctor what prescription and nonprescription drugs you are taking, especially high blood pressure medication, tranquilizers, and beta blockers.
3. Ask your doctor for advice about the safe use of alcohol; it can make side effects worse.
4. Do not allow anyone else to take this medication.

Storage Conditions :
1. Keep this medication in the container it came in, tightly closed, and out of the reach of children.
2. Store it at room temperature, away from excess heat or cold.

Isoproterenol Inhalation

Generic Name : Isoproterenol Inhalation

Why it is prescribed (Indications) : Isoproterenol, a bronchodilator, relaxes and opens the air passages to the lungs, making it easier to breathe. It is used to relieve asthma attacks and breathing problems caused by emphysema, bronchitis, and other lung diseases.

When it is to be taken : Isoproterenol is usually used every three or four hours, four to six times a day. Follow the instructions on your prescription label carefully. Isoproterenol begins to work immediately and goes on working for one hour.

How it should be taken : How it should be taken: Isoproterenol comes as an aerosol for oral inhalation with a special inhaler. Your prescription label tells you how many inhalations to take at each dose, usually one or two. To use the inhaler, follow the instructions that come wi

Special Instruction :
1. Rinse the mouthpiece with warm water once a day. If this medication loses its effectiveness or if your condition worsens, stop using isoproterenol and contact your doctor immediatley.
2. Do not use the inhaler more often or take more inhalations at each dose than as directed.
3. Increasing your dose can be dangerous and can decrease the drug's effectiveness.
4. If your sputum thickens or changes colour from clear white to yellow, green, or gray, contact your doctor; these changes may be signs of an infection.

Side Effects :
1. Pink-coloured saliva and sputum. This effect is harmless.
2. Dry mouth and throat. Rinse your mouth with water after each treatment.
3. Irritated air passages, nervousness, restlessness, insomnia, anxiety, fear, tension, excitement contact your doctor if these are severe or persist.
4. Increased difficulty breathing; fast heartbeat; palpitations; red, itchy, clammy skin; wheezing; shortness of breath; faintness. Stop using isoproterenol and contact your doctor immediately.

Other Precautions :
1. Before you use isoproterenol, tell your doctor if you are pregnant or breast-feeding or if you have kidney or heart disease, high blood pressure, an overactive thyroid gland, or diabetes.
2. Isoproterenol can affect the way your body responds to certain drugs. Before using isoproterenol, tell your doctor what prescription and nonprescription medications you are taking, especially ergotamine and medictions for asthma, high blood pressure, or heart disease.
3. Before using isoproterenol, tell your doctor if you ever had a bad reaction to albuterol, ephedrine, epinephrine, isoetharine, metaproterenol, phenylephrine, phenylpropanolamine, pseudoephedrine, or terbutaline.
4. Many nonprescription medications contain these drugs e.g., diet pills and medication s for colds or asthma, so check the labels carefully.
5. Do not take nay of these drugs without consulting your doctor. If your doctor directs you to take any of them, do not take them within four hours of taking isoproterenol.
6. Before having surgery with a general anesthetic, tell the doctor that you use isoproterenol.
7. Do not allow anyone else to take this medcation.

Storage Conditions :
1. Keep this medication out of the rech of children.
2. Store it at room temperature, away from excess heat.

Isoniazid

Generic Name : Isoniazid

TradeName : Isokin, Isonex, Solonex

Why it is prescribed (Indications) : Isoniazid is used alone or with other drugs to treat tuberculosis (TB) and to prevent it in people who have had contact with tuberculosis bacteria. It eliminates only active or growing bacteria. Since the bacteria may exist in a resting or nongrowing state for long periods, therapy with isoniazid and other antituberculosis drugs must be continued for a long time, usually six to 12 months.

When it is to be taken :
1. Isoniazid usually is taken once a day, preferably on an empty stomach.
2. Follow the instructions on your prescription label carefully.
3. Isoniazid must be taken regularly to be effective. Take all of the doses prescribed.
4. To avoid missing doses, try to take this medication at the same time yo perform some other regular daily activity, such as brushing your teeth at bedtime.

How it should be taken : Isoniazid comes in the form of tablets and oral liquid. Your prescription lebel tells you how much to take at each dose. You may obtain a specially marked measuring spoon to be sure of an accurate dose of the liquid.

Special Instruction :
1. Do not stop taking isoniazid without consulting your doctor. Stopping the drug can allow your infection to return.
2. Keep all appointments with your doctor and the laboratory so that your response to the drug can be evaluated.
3. Once your doctor tells you to stop taking isoniazid, keep all appointments so that your doctor can check that the infection does not return.
4. If you take aluminium hydroxide gel, an antacid, take it at least one hour after taking isoniazid.
5. Take the missed dose as soon as you remember it. However, if you remember a missed dose near the time you are to take the next one, omit the missed dose and take only your regularly scheduled dose.

Side Effects :
1. Blurred vision, vision problems, eye pain. Contact your doctor. you probably should have your eyes examined.
2. Tingling, prickling, burning, tightness, pulling, and drawing feeling in hands and feet. Contact your doctor. Your doctor may prescribe pyridoxine i.e., vitamin B6 to treat or prevent this problem.
3. Skin rash, fever, swollen glands, fatigue, weakness, nausea, vomiting, loss of appetite. Contact your doctor immediately.

Other Precautions :
1. Before taking isoniazid, tell your doctor if you ever were treated for tuberculosis or had a bad reaction to isoniazid or if you have a history of kidney or liver disease, diabetes, or alcoholism.
2. Tell your doctor what prescription and nonprescription drugs you are taking, especially aluminium hydroxide gel, disulfiram, and phenytoin.
3. Diabetics should not use Clinitest to test their urine for sugar because isoniazid can cause false results in this test.
4. Do not allow anyone else to take this medication.

Storage Conditions :
1. Keep this medication in the container it came in, tightly closed, and out of the reach of children.
2. Store it at room temperature, away from light and excess heat.
3. Do not allow the liquid to freeze

Isoetharine

Generic Name : Isoetharine

Why it is prescribed (Indications) : Isoetharine, a bronchodilator, relaxes and opens the air passages to the lungs, making it easier to breathe. It is used to treat asthma attacks and breathing problems caused by bronchitis, emphysema, and other lung diseases.

When it is to be taken : Isoetharine is used as needed but usually should not be used more often than every four hours. Follow the instructions on your prescription label carefully. Isoetharine starts to work immediately and goes on working for up to four hours.

How it should be taken : Isotharine comes as a liquid to be inhaled with a special hand-bulb nebulizer and as an aerosol for oral inhalation with a special inhaler. Your prescription label tells you how many inhalations to take at a time. To use the aerosol inhaler or liquid nebu

Special Instruction :
1. If this medication loses its effectiveness or if your condition worsens, stop using isoetharine and contact your doctor immediately.
2. Do not use this medication more often or take more inhalations at each dose than as directed.
3. Increasing your dose can be dangerous and can decrease the drug's effectiveness.
4. If your sputum thickens or changes colour from clear white to yellow, green, or gray, contact your doctor; these changes may be signs of an infection.
5. Do not use the liquid if it is discoloured; it should be clear and colourless.

Side Effects :
1. Irritated air passages, cough, tremors, weakness, nausea, vomiting, headache, excitement, dizziness, anxiety, tension, restlessness, insomnia. Contact your doctor if these effects are severe or persist.
2. Increased difficulty breathing; wheezing; shortness of breath; red, itchy, skin; faintness; fast heartbeat; palpitations. Contact your doctor immediately.

Other Precautions :

1. Before using isoetharine, tell your doctor what prescription and nonprescription medications you are taking, especially beta blockers like atenolol, labetalol, metoprolol, nadolol, pindolol, propranolol, and timolol and other asthma medications.
2. Before using isoetharine, tell your doctor if you ever had a bad rection to albuterol, ephedrine, epinephrine, isoproterenol, metaproterenol, phenylephrine, phenylpropanolamine, pseudoephedrine, or terbutaline.
3. Many nonprescription medications contain these drugs e.g., diet pills and medications for colds or asthma, so check the labels carefully. Do not take any of these drugs without consulting your doctor.
4. If your doctor directs you use any of them, do not take them within four hours of taking isoetharine.
5. Before you use isoetharine, tell your doctor if you have an overactive thyroid gland, high blood pressure, or heart disease or if you are pregnant or breast-feeding.
6. Do not alow anyone else to take this medication.

Storage Conditions :
1. Keep this medcation out of the reach of children.
2. Store it at room temperature, away from excess heat and light.
3. Avoid puncturing the aerosol container

Iron - III Hydroxide Polymaltose Complex - IPC

Generic Name : Iron - III Hydroxide Polymaltose Complex - IPC

TradeName : ANIFOL, BALOFER, FACER, ELERON, FEMED, FERED, FERITIN, FERITONE,
FERIUM, FERRI, GILFER, HAEM UP -PM, HAEM UP DPS, MUMFER, PREFER, UFER,
WAFER, TRIFER

Why it is prescribed
(Indications) : It is a water soluble, iron oxide, macromolecular complex of poly nuclear iron (III) hydroxide and partially hydrolysed dextrin ( Polymaltose)

When it is to be taken : Treatment of latent iron deficiency and iron deficiency anaemia. Prevention of iron and folic acid deficiency before, during and afetr pregnancy. For prophylactic therapy of iron deficiency to cover the recommended daily dietary allowance during pregnancy and lactation.

How it should be taken : Dosage and duration of therapy are dependent upon the extent of iron deficiency. It should be taken during or immediately after meals.

Side Effects :
There is a very low incidence of adverse effects. Occasionally gsatrointestinal symptoms such as sensation of repletion, pressure in the epigastric region, nausea, constipation or diarrhoea can occur.

Storage Conditions :
it is important to keep iron supplements tightly capped and away from childrens reach

IRINOTECAN

Generic Name : IRINOTECAN

TradeName
: IRNOCAM vial TORSIRIN vial

Why it is prescribed (
Indications) : This medication is prescribed for colon or rectal cancer, either alone or in combination with other medications. It is an anti cancer drug. It stops the growth of cancer cells.

When it is not to be taken (Contraindications) : Inflammatory bowel disease, bowel obstruction, severe liver impairment, pregnancy and lactation. Irinotecan hydrochloride injection is contraindicated in patients with a known hypersensitivity to the drug.

When it is to be taken
: IV 125 mg/m2 once wkly for 4 week, followed by a 2 week rest period.

How it should be taken
: This medication available in the form of liquid to be given over 90 minutes intravenously (into a vein) by healthcare providers, once in a week.

Special Instruction :

*It may make you dizzy or affect your vision
. Do not drive a car or operate machinery while taking this medication. *Consult with your doctor before you receive any vaccinations during your treatment with this medication. *Caution needed for patients with diabetes, fructose intolerance, or liver, lung, or kidney disease. *Report any symptoms of fluid or electrolyte loss to your doctor.*It may increase the level of plasma-bilirubin concentration and lead to severe decreased bone marrow activities.

Side Effects :
CENTRAL NERVOUS SYSTEM
Dizziness; drowsiness; trouble sleeping; weakness; headache; lightheadedness; confusion; dizziness, discomfort.
GI
Constipation; gas; increased salivation; indigestion; loss of appetite; mouth sores; nausea; stomach pain/cramps; dehydration; diarrhea.
SKIN
Hair loss; sweating; redness, or swelling at the injection site.
MUSCLE AND BONE
Back pain; numbness of an arm or leg; one-sided weakness; pain in the groin or lower legs.
MISCELLANEOUS
Cough; flushing; tearing; weight loss; chest pain; fainting; fever, chills, shortness of breath.

Other Precautions :
*Avoid use of laxatives because of the risk of increased diarrhea. *Avoid extravasations.

IRBESARTAN

Generic Name : IRBESARTAN

TradeName : APROVEL tab IRBEST tab IROVEL tab IROVEL-H tab XARB tab XARB-H tab

Why it is prescribed (Indications) : It is used alone or in combination with other medications to treat high blood pressure. It is also used to treat kidney disease caused by diabetes in patients with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control blood sugar) and high blood pressure. It is an angiotensin II receptor blocker (ARB). It works by relaxing blood vessels. This helps to lower blood pressure.

When it is not to be taken
(Contraindications) : Hypersensitivity; pregnancy and lactation.

When it is to be taken
: Oral Hypertension Adult: 150 mg once daily, increased to 300 mg once daily if necessary. For patients with intravascular volume depletion: Initially, 75 mg once daily. Child: 6-16 yr: 75 mg once daily increased to 150 mg if necessary. Elderly: >75 yr: Initially 75 mg once daily. Renal impairment: Haemodialysis: Initially, 75 mg once daily. Oral Diabetic nephropathy in Type 2 diabetes mellitus Adult: 150 mg once daily, increased to 300 mg once daily if necessary.

How it should be taken
: It comes as a tablet to take by mouth. It is usually taken once a day with or without food.

Special Instruction :

*This medication may not work as well in Black patients. Discuss any questions or concerns with your doctor. *Dehydration; excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your healthcare provider immediately. *Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." *Caution needed while using with children, elederly patients, and in pregnancy
women. *Lab tests, including blood pressure, blood electrolyte levels, and heart, kidney, or liver function, may be performed while using this medication.

Side Effects :

HEART
Chest pain, fast heart beat, edema.
CENTRAL NERVOUS SYSTEM
Headache, anxiety/nervousness, dizziness.
GI
Diarrhea, stomach upset, heartburn, abdominal pain, nausea/vomiting.
RESPIRATORY
Upper respiratory tract infection, influenza, runny nose, sinus abnormality.
MISCELLANEOUS
Musculoskeletal pain/trauma, fatigue, UTI, rash
.
Other Precautions :
Avoid abrupt withdrawal.

Storage Conditions :
Store at 25°C. Store it in air tight container and keep away from childre

Ipratropium Bromide

Generic Name : Ipratropium Bromide

TradeName : Ipratop, Ipravent,

Why it is prescribed
(Indications) : Ipratropium, a bronchodilator, opens the air passages to the lungs, making it easier to breathe. It is used - on a regular schedule - to prevent bronchospam caused by chronic bronchitis, emphysema, and other lung diseaes. It is not used to treat bronchospasm attacks when a rapid response is required.

When it is to be taken : Ipratropium usually is used for four times a day on a regular schedule. Follow the instructions on your prescription label carefully.

How it should be taken :
1. Ipratroplum comes as an aerosol for oral inhalation with a special inhaler. Your prescription label tells you how many inhalations to take at each dose, usually two.
2. Before you take ipratropium by inhalation, read the written instructio

Special Instruction :
1. Once a day, remove the container of drug from the plastic mouthpiece, wash the mouthpiece with warm tap water, and dry it thoroughly.
2. Ipratropium must be used regularly to be effective. However, do not use this medication more often or take more inhalations at each dose than your doctor has directed.
3. Your doctor may instruct you to take some additional inhalations if required; however, do not inhale more than 12 inhalations in 24 hours.
4. Take the missed dose as soon as you remember it and take any remaining doses for that day at evenly spaced intervals. However, if you remember a missed dose near the time for your next scheduled dose, take only the scheduled dose. Do not take a double dose.

Side Effects :
Nervousness, dizziness, headache, nausea, cough, mouth or throat irritation, dry mouth, skin ras, palpitations, blurred vision. Contact your doctor if these effects persist or are severe.

Other Precautions :
1. Women who are pregnant or breast-feeding should inform their doctors.
2. Before using ipratropium, tell your doctor what prescription and nonprescription medications you are taking and if you ever had a bad reaction to atropine.
3. Tell your doctor if you have prostate problems, difficylty urinating, or glaucoma.
4. Avoid getting the spray into your eyes.
5. Temporary blurring of vision
can result.
6. Do not allow anyone else to use medicatiion.

Storage Conditions :
1. Keep ipratropium out of the reach of children.
2. Store it at room temperature, away from excess heat and humidity.
3. Avoid puncturing the container.

Iodine

Generic Name : Iodine

TradeName : Collosol iodine oral

Why it is prescribed
(Indications) : Exact mechanism is not known. It inhibits hormone release. It is fastest acting thyroid inhibitor. On regular administration, antithyroid effect is seen in 2 weeks.

When it is to be taken : 5-10ml diluted in water TD.

How it should be taken :
It comes in the form of 100ml liquid.

Special Instruction :
If the dosage is increased, goiter and hyperthyroidism occurs. Acne may flare. Tell your doctor if you are hyper sensitivity to drug.

Side Effects :
Angiodema, fever, thrombocytopenia, arthralgia, lymphadenopathy, salvation, swelling of lips and eyelids.

Other Precautions :

Contraindicated in case of pregnancy and lactation. May be used in older age.

Storage Conditions :
Store at room temperature.

Interferon Alpha-2B

Generic Name : Interferon Alpha-2B

TradeName : Shanferon.Viraferon.

Why it is prescribed : It blocks viral and RNA development.It is used in the treatment of
Chronic Hepatitis B and C.
AIDS related Kaposi's sarcoma.Different types of tumours.
Multiple myeloma and melanomas.
Chronic myeloid and Hairy cell leukemia.

When it is to be taken : The treatment varies for the different conditions.

How it should be taken : It is given as intramuscular or subcutaneous injections.

Special Instruction :

To be used with caution in severe renal or hepatic impairment,diabetes,pregnancy and lactation.The doctor must be informed about other diseases or medications.Blood counts,and renal and hepatic function tests must be monitored regularly.

Side Effects :
Flu-like symptoms,alopecia,nausea,anxiety,rash,confusion.

Other Precautions :
Contraindicated in hypersensitivity.

Storage Conditions :

To be stored under refridgeration.

INSULIN DETEMIR

Generic Name : INSULIN DETEMIR

TradeName : LEVEMIR FLEXPEN FlexPen

Why it is prescribed
(Indications) : This medication is prescribed for diabetes in patients with need of insulin to control their diabetes. It is a long-acting insulin. It helps to control the levels of glucose (sugar) in the blood. It works by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar.

When it is not to be taken (Contraindications) : Do not admin by Intravenous, Intra muscular or via insulin infusion pump. Hypersensitivity to any component.

When it is to be taken : SC In insulin-naive patients with type 2 diabetes who are not well controlled on oral antidiabetic drugs: Initial: 0.1-0.2 u/kg once daily in the evening or 10 u 1-2 times/day, adjust subsequently based on glucose control. In patients on basal insulin only: May substitute with insulin detemir on a unit-for-unit basis based on the current basal insulin dosage; adjust subsequently to achieve glucose targets.

How it should be taken : It comes as a solution (liquid) to inject subcutaneously (under the skin). It is usually injected once a day, with the evening meal or at bedtime, or twice a day, in the morning and in the evening with the evening meal or at bedtime.

Special Instruction :
 It may affect liver or kidney functions.  Regular monitoring of blood glucose and HbA1c.  Continuous rotation of the injection site within a given area to reduce injection site reactions (allergic reactions that result in cutaneous necrosis)  Inform your doctor about your pregnancy and lactation

Side Effects :
CENTRAL NERVOUS SYSTEM
Headache, neuropathy, seizure, sensory disturbances.
SKIN
Inflammation of injection site, itching, rash, skin disorder.
EYE AND ENT
Blurred vision, inflammation of nasopharynx.
GI
Abdominal pain, diarrhea, nausea.
GENITOURINARY
Urinary tract infection.
HYPERSENSITIVITY
Hypersensitivity reaction (including anaphylaxis, angioedema, fast pulse, hypotension, rash, shortness of breath, sweating), insulin antibody production.
LAB TESTS
Elevated alkaline phosphatase.
METABOLIC-NUTRITIONAL
Low blood sugar, low potassium level, weight gain.
RESPIRATORY
Upper respiratory tract infection.
MISCELLANEOUS Accidental injury, chest pain, absent reflexes, influenza, peripheral edema.

Other Precautions :
It is not to be used in insulin infusion pumps.

Storage Conditions :
Subcutaneous: Unopened preparation: Store between 2-8°C (36-46° F). Do not freeze.

INSULIN ASPART

Generic Name : INSULIN ASPART

TradeName
: NOVOLOG inj

Why it is prescribed (Indications) : This medication is prescribed for diabetes mellitus. It is used with other medium- or long-acting insulin product injected just below the skin to control high blood sugar. It helps sugar (glucose) get into cells.

When it is not to be taken
(Contraindications) : Low blood sugar, allergy to insulin aspart, excipients.

When it is to be taken : SC Usual range: 0.5 to 1 u/kg/day

How it should be taken : It comes as a solution (liquid) to inject subcutaneously (under the skin). It is usually injected immediately before meals (5 to 10 minutes before eating). It can also be infused under the skin using an external insulin pump.

Special Instruction :
*Avoid changing the type of insulin, without health care provider’s advice. *It may harm liver or kidney functions, pregnancy; lactation. *Monitor serum glucose, potassium, electrolytes, HbA1c and lipid profile. *Precautions should be taken during concomitant illness especially infections low level potassium in blood. *Change the injection site within same area.*Developing a fever or infection, eating significantly more than prescribed, or missing your dose of insulin may cause high blood sugar (hyperglycemia).

Side Effects :
METABOLIC- Low blood sugar, weight gain, low potassium level in blood.
CENTRAL NERVOUS SYSTEM- Headache, neuropathy, seizure, sensory disturbances.
SKIN- Lipodystrophy (from repeated insulin injection into same site), itching, rash, skin disorder.
ALLERGIC REACTIONS- Rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; wheezing.
GI- Extreme thirst, extreme hunger, dry mouth, nausea and vomiting.
EYE- Diabetic retinopathy, inflammation of nasopharynx.
GENITOURINARY- Urinary tract infection.
HEART- Fast or irregular heart beat.
RESPIRATORY- Upper respiratory tract infection
LOCAL- Catheter occlusions, infusion-site reactions, itching at injection site, redness, swelling.
LAB TESTS- Elevated alkaline phosphatase.
MISCELLANEOUS- Accidental injury, chest pain, absent reflexes, influenza, onychomycosis ( fungal infection of the nail), peripheral edema.

Other Precautions :
*If you will be traveling across time zones, consult your doctor concerning adjustments in your insulin schedule. *Avoid alcohol consumption while taking this medication.

Storage Conditions :

Store unopened vials, cartridges, and pens in the refrigerator. Do not freeze.

Insulin

Generic Name : Insulin

TradeName : Actraphane HM Penfill, Actrapid, Actrapid HM, Actrapid MC, Human actrapid, Human insulatard, Human mixtard, Human monotard, Human prodica, Human rapidica, Human rapimix, Humanzinulin, Huminsulin, Huminsulin-N, Huminsulin-R, Iletin – N, Iletin - R, Insulatard, Insula

Why it is prescribed (Indications) : Insulin is a hormone produced in the pancreas. Insulin is necessary to move sugar from the blood into other body tissues where it is needed for energy. Insulin also helps the body to metabolize carbohydrates, fats, and proteins from the diet. In a person with diabetes, the pancreas does not produce enough insulin for the body's needs, so additional insulin is required. It must be injected because stomach acid would destroy it if taken orally. Insulin controls - but does not cure - diabetes. It must be taken regularly. People with diabetes can gradually develop serious nerve, blood vessel, kidney, and eye problems, especially if the diabetes is not controlled properly.

When it is to be taken :
Your doctor will determine how often and at what time of day to inject yor insulin, as well as what type of insulin will best control the level of sugar in your blood. The different types of insulin vary as to how quickly they start to work and how long they go on reducing the amount of blood sugar. For example, rapid-acting insulins, such as regular insulin and Semilente, start to work in 30 to 60 minutes and go on working for 5 to 16 hours; long-acting insulins, such as Ultralente, start to work in four to eight hours and continue working for 36 hours.

How it should be taken :
1. Insulin is usually given by subcutaneous (beneath the skin) injection. The amount of insulin you need depends on diet, other diseases, exercise, and drugs and may change with time.
2. All insulin bottles are marked with large black letter

Special Instruction :
1. Because diabetics are susceptible to infections, maintain good personal hygiene, particularly dental and foot care. Bathe daily; keep all cuts, scratches and open sores clean. Visit an op
2. Visit an ophthalmologist at least once a year.
3. To monitor the effectiveness of insulin, measure the amount of sugar in your blood or urine. For these measurements, you will need special paper tapes, tablets, or plastic strips that change colour depending on how much sugar is present.
4. You also can use a special device called glucometer to measure the amount of sugar in your blood. Your doctor also may ask you to test your urine for ketones, substances present when diabetes is not under control.
5. Follow your doctor's instructions for testing your urine and blood and for recording the results accurately.
6. If your blood sugar is high or if sugar or ketones are present in your urine, contact your doctor.
7. Do not change your insulin dose without consulting your doctor.
8. Tell your doctor if you smoke or if you change your smoking habits while taking insulin. Your dose may need to be adjusted.
9. Special Dietary Instructions should be followed : To control diabetes, you must follow a strict diet in addition to taking insulin regularly. Your insulin dose is based in part on your intake of calories from food. Follow your doctor's instructions concerning diet, body weight, and exercies.
10. Alcoholic beverages may cause hypoglycemia i.e.,low blood sugar. Alcoholic beverages also contain calories; these calories should be taken into consideration when planning your diet.
11. When you first start taking insulin, ask your doctor what to do if you forget to take a dose at the correct time. Write down these instructions so that you can refer to them later.

Side Effects :
1. Low blood sugar i.e., hypoglycemia as a result of taking too much insulin or exercising strenuously: headache, nausea, sweating, hunger, paleness, numb mouth, tingling fingers, tremors, blurred or double vision, chills, muscle weakness, fatigue, irritability, mental confusion, uncontrolled yawning, shallow breathing, palpitations, fast hearbeat. These reactions are most common in the late afternoon or during the night when insulin is working hardest. Drink fruit juice or eat lump sugar or something containing sugar. You may wish to carry glucose with you in case you have this reaction. Glucose comes in chewable tablets and gel and is available without a prescriptiion.
2. High blood sugar i.e., hyperglycemia as a result of not taking enough insulin: frequent urination, thirst, headache, weakness, nausea, dizziness. Often it is difficult to tell if your blood sugar is too high or too low. If possible, test your blood sugar with a glucometer. Otherwise, call your doctor. If you feel faint, instruct someone to take you to your doctor or a hospital right away.

Other Precautions :
1. Tell your doctor if you ever had an allergic reaction to beef or pork insulin, if you are pregnant, and if you have any medical problem such as thyroid, liver, or kidney disease or an infection.
2. Before you take insulin, tell your doctor what prescription and nonprescription drugs you are taking.
3. Other medications can affect the action of insulin and can cause inaccurate results in urine tests for sugar or ketones.
4. Do not take nonprescription medications, particularly cold and allergy medications, and medications that contain alcohol or sugar without consulting your doctor.
5. Wear or carry identification indicating that you have diabetes. Write down your doctor's name, telephone number, and the type and dose of insulin you are taking on the identification card.
6. Do not allow anyone else to take this medication.

Storage Conditions :
1. Store insulin in the refrigerator.
2. Never allow insulin to freeze; do not use insulin that has been frozen. 3. Never heat insulin to warm it.

Infliximab

Generic Name : Infliximab

Pronunciation : in flix' i mab

TradeName : Remicade

Why it is prescribed (Indications) : This medication is prescribed for autoimmune disorders, joint pains, Crohn's disease, inflammatory bowel disease, ankylosing spondylitis, psoriasis. It blocks the action of TNF-alpha, a substance in the body that causes inflammation

When it is not to be taken
(Contraindications) : Hypersensitivity to murine proteins or other components of product; administration of more than 5 mg/kg to patients with moderate or severe heart failure.

When it is to be taken : IV 5 mg/kg infusion followed by additional 5 mg/kg at 2 and 6 week after the first infusion, then every 6 week thereafter

How it should be taken : This medication available in the form solution for to be injected intravenously by a doctor or nurse. It is usually given every 2 to 8 weeks. It will take about 2 hours for absorption.

Special Instruction :
: *Avoid vaccination while taking this medication*caution should be exercised in patients with history of hepatitis B. *It may develop an active infection while using this medication.

Side Effects :
GI:
Stomach pain, nausea, loss of appetite, and blood in stool
Heart:
Chest pain, shortness of breath.

Miscellaneous:
Headache, runny nose, vaginal itching, flushing, rash, joint pain, seizures.

Other Precautions :
It may affect blood clots, avoid unusual bruising or bleeding.

Storage Conditions :
Store vials of powder for injection in refrigerator (36° to 46°F). Do not freeze.

Indomethacin

Generic Name : Indomethacin

TradeName : Artisid, Idicin, Indocap, Indoflam, Inmecin, Inmecin-R, Inocin, Microcid, Recticin

Why it is prescribed (Indications) : Indomethacin relieves the pain, inflammation, swelling, and stiffness caused by certain types of arthritis and other medical problems.

When it is to be taken
: Indomethacin capsules and liquid are usually taken two to four times a day; extended-release capsules are taken one or two times a day. Although arthritis symptoms may improve after four to six days, you may have to take this drug regularly for one month before feeling its full effect. If you have persistent night pain or morning stiffness, take one of your doses at bedtime.

How it should be taken : Indomethacin comes in the form of regular capsules, extended-release or long-acting capsules, and oral liquid. Your prescription label tells you how much to take at each dose. Extended-release capsules should be swallowed whole; do not open them to mix th

Special Instruction :
1. Indomethacin can affect mental alertness and coordination. Do not drive a car or operate dangerous machinery until you know how it affects you.
2. Take only the amount of medication prescribed. If you think you need more to relieve your symptoms, contact your doctor.
3. Keep all appointments with your doctor and the laboratory. Your doctor may wish to adjust your dose, and you may have blood tests.
4. Take the missed dose as soon as you remember it. However, if you remember a missed dose near the time you are to take the next dose, take only the regularly scheduled dose. Do not take a double dose.

Side Effects :
1. Nausea, vomiting, indigestion, stomach pain. Take the medication immediately after meals, with food, or with antacids.
2. Do not drink alcoholic beverages. Contact your doctor if these effects persist or severe.
3. Headache, dizziness, drowsiness, ringing in the ears. Contact your doctor.

Other Precautions :
1. Certain drugs can affect the way your body responds to this medication. Before you take indomethacin, tell your doctor what prescription and nonprescription drugs you are taking, especially aspirin, anticoagulants, lithium, probenecid, and high blood pressure medications.
2. Tell your doctor if you ever had gastritis or bleeding from the stomach or rectum, ulcers, diverticulitis, kidney disease, heart disease, high blood pressure, epilepsy, Parkinson's disease, diabetes, or mental disorder.
3. Women who are pregnant or breast-feeding should tell their doctors before taking indomethacin.
4. If you ever had a bad reaction to aspirin or other arthritis medications, tell your doctor before taking indomethacin.
5. Do not allow anyone else to take this medication.

Storage Conditions :
1. Keep this medication in the container it came in and out of the reach of children.
2. Store it at room temperature.

Indinavir

Generic Name : Indinavir

TradeName : INDIVAN-400, INDIVIR

Why it is prescribed
(Indications) : It is an inhibitor of the enzyme human immunodefeciency virus protease which is required for the proteolytic cleavage of the viral polyprotein precursors into the individaul functional proteins found in infectious HIV

When it is to be taken : Treatment of HIV infection in combination with antiretroviral agents

How it should be taken : Adults: 800 mg orally every 8 hours with water 1 hour before or 2 hours after a meal.Patient should drink atleast 1.5 litres of liquids in 24 hours.

Special Instruction :

Contraindications:Hypersensitivity. Avoid concurrent use with terfenadine, cisapride, astemi-zole, triazolam, midazolam, or ergot derivatives.

Side Effects :
Nausea, vomiting, diarrhoea, abdominal discomfort, dry mouth, taste disturbances. Headache, dizziness, insomnia, myalgia, asthenia, paraesthesia, rash, pruitus, dry skin, hyperpigmentation, nephrolithiasis, dysuria, haematuria, crystalluria, proteinuria, elevated liver enzymes and bilirubin, hepatitis, neutropenia, haemolytic anaemia, hyperglycaemia.

Other Precautions :
Hepatic impairment, ensure adequate hydration to ensure adequate hydration to reduce risk of nephrolithiasis, haemophilia ( possible increased bleeding). Monitor blood glucose levels.Pregnancy: Use only if potential benefit justifies potential risk to the fetus. Lactation: Contraindicated. Elderly: May be used.

Storage Conditions :
Keep out of the reach of children. Store away from heat and direct light. Indinavir capsules are very sensitive to moisture. Keep them in their original container and leave the drying packet in the container. Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.