Infliximab

Generic Name : Infliximab

Pronunciation : in flix' i mab

TradeName : Remicade

Why it is prescribed (Indications) : This medication is prescribed for autoimmune disorders, joint pains, Crohn's disease, inflammatory bowel disease, ankylosing spondylitis, psoriasis. It blocks the action of TNF-alpha, a substance in the body that causes inflammation

When it is not to be taken (Contraindications) : Hypersensitivity to murine proteins or other components of product; administration of more than 5 mg/kg to patients with moderate or severe heart failure.

When it is to be taken : IV 5 mg/kg infusion followed by additional 5 mg/kg at 2 and 6 week after the first infusion, then every 6 week thereafter

How it should be taken : This medication available in the form solution for to be injected intravenously by a doctor or nurse. It is usually given every 2 to 8 weeks. It will take about 2 hours for absorption.

Special Instruction :
: *Avoid vaccination while taking this medication*caution should be exercised in patients with history of hepatitis B. *It may develop an active infection while using this medication.

Side Effects :
GI:
Stomach pain, nausea, loss of appetite, and blood in stool
Heart:
Chest pain, shortness of breath.

Miscellaneous:
Headache, runny nose, vaginal itching, flushing, rash, joint pain, seizures.

Other Precautions :
It may affect blood clots, avoid unusual bruising or bleeding.

Storage Conditions :
Store vials of powder for injection in refrigerator (36° to 46°F). Do not freeze.