Tau/Aß42 : labtest

Why Get Tested?
To help discriminate between Alzheimer's Disease and other forms of early-onset dementia
When to Get Tested?
These tests may be ordered along with cognitive and brain-imaging tests in patients who demonstrate some form of dementia. These tests are not routine laboratory tests and are available only in research settings or memory clinics.
Sample Required?
A sample of cerebrospinal fluid collected using a spinal tap

How is it used?
Tests for Tau protein and Aß42 may be used as supplemental tests to help establish a diagnosis of Alzheimer's Disease.
If someone has symptoms of dementia, such as memory loss, behavioral changes, and decreased ability to perform daily life functions, the doctor will do a thorough work-up to try to determine the cause. This work-up may include a variety of cognitive tests (Minimal Mental State Exam) to assess memory and possibly PET scanning tests (Pittsburgh Compound-B) of the brain to look for abnormalities.

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