ROSUVASTATIN

Generic Name : ROSUVASTATIN

TradeName : BESTOR tab FORTIUS tab FORTIUS-20 tab LDNIL film-coated tab NOVASTAT tab RAZEL tab ROSTAR tab ROSUVAS tab ROSUVASTAT tab ROSYN tab ROVALIP tab ROZAVEL tab ROZUCOR tab TURBOVAS tab ZYROVA tab

Why it is prescribed (Indications) : This medication is used to reduce the cholesterol in patients with obesity problem. It is a HMG-CoA reductase inhibitor (statin). It slows the production of cholesterol in the body.

When it is not to be taken (Contraindications) : It may cause severe kidney failure, active liver disease, unexplained persistent elevations of serum transaminases; hypersensitivity, harmful in pregnancy
, lactation (breast feeding).

When it is to be taken : Oral: Initial: 5 to10 mg/day may increase slowly to 20 mg/day if needed. Max: 40 mg/day

How it should be taken : Rosuvastatin comes as a tablet to take by mouth. It is usually taken once a day with or without food.

Special Instruction :
• Not to be used in patient with acute, serious condition suggestive of muscular diseases(myopathy) or predisposing to the development of kidney failure secondary to rapid breakdown of skeletal muscle(rhabdomyolysis) e.g. sepsis, hypotension, major surgery, trauma, severe metabolic, endocrine and electrolyte disorders or uncontrolled seizures. • Caution should be exercised with patients with history of liver disease and alcoholism. • Discontinue treatment if there is marked or persistent increase in serum aminotransferase concentrations, significant increase in creatinine phosphokinase or evidence of muscular diseases

Side Effects :
CENTRAL NERVOUS SYSTEM:
Headache, dizziness, tingling, lack of energy, sleeplessness, depression.
GI
Nausea, vomiting, abdominal pain, constipation
MISCELLANEOUS:
Muscle pain, chest pain, swelling of tissues, skin rash, , protein in urine.

Other Precautions :
Avoid changing dosage with out consulting health care providers. Monitor liver function, kidney function, and cholesterol level in blood regularly.

Storage Conditions :
Store at room temperature(20-25°C).