Why Get Tested?
To help investigate inappropriate blood clot formation, to help determine the cause of recurrent miscarriage, or as part of an evaluation for antiphospholipid syndrome
When to Get Tested?
When you have had one or more unexplained venous or arterial thrombotic episodes; when you have had recurrent miscarriages, especially in the second and third trimesters
Sample Required?
A blood sample drawn from a vein in your arm
How is it used?
Tests for IgG and IgM cardiolipin antibodies are frequently ordered to help determine the cause of an unexplained thrombotic episode, recurrent miscarriage, or thrombocytopenia. They may be ordered along with lupus anticoagulant testing to help investigate the cause of a prolonged PTT (activated partial thromboplastin time), especially if clinical findings suggest that the patient may have SLE or another autoimmune disorder. If the primary test results are unremarkable but clinical suspicions still exist, then IgA cardiolipin antibody testing may be ordered.
If one or more of the classes of cardiolipin antibodies is detected, then the same test(s) are usually repeated at least 6 weeks apart to help determine whether their presence is persistent or temporary. If a patient with a known autoimmune disorder tests negative for cardiolipin antibodies, they may be retested later as these antibodies may develop at any time in the future.
To help investigate inappropriate blood clot formation, to help determine the cause of recurrent miscarriage, or as part of an evaluation for antiphospholipid syndrome
When to Get Tested?
When you have had one or more unexplained venous or arterial thrombotic episodes; when you have had recurrent miscarriages, especially in the second and third trimesters
Sample Required?
A blood sample drawn from a vein in your arm
How is it used?
Tests for IgG and IgM cardiolipin antibodies are frequently ordered to help determine the cause of an unexplained thrombotic episode, recurrent miscarriage, or thrombocytopenia. They may be ordered along with lupus anticoagulant testing to help investigate the cause of a prolonged PTT (activated partial thromboplastin time), especially if clinical findings suggest that the patient may have SLE or another autoimmune disorder. If the primary test results are unremarkable but clinical suspicions still exist, then IgA cardiolipin antibody testing may be ordered.
If one or more of the classes of cardiolipin antibodies is detected, then the same test(s) are usually repeated at least 6 weeks apart to help determine whether their presence is persistent or temporary. If a patient with a known autoimmune disorder tests negative for cardiolipin antibodies, they may be retested later as these antibodies may develop at any time in the future.
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