IFOSFAMIDE

Generic Name : IFOSFAMIDE

TradeName : HOLOXAN inj HOLOXAN-UROMITEXAN vial IFEX-M inj IFEX-M vial IFOCIP inj IFOXAN WITH MESNA INJ COMBI-pack IPAMIDE inj ISOXAN combipackvial

Why it is prescribed (Indications) : It is used to treat certain types of cancer (breast cancer, lymph cancer, lung cancer) in combination with other medicines.

When it is not to be taken (Contraindications) : It may lead to hypersensitivity; severe bone-marrow depression, pregnancy and breast feeding.

When it is to be taken : IV Lymph cancer; Solid tumours Different licensed dosage regimens are available. 8 to12 g/m2 divided over 3 to 5 days, repeat course 2 to4 wkly. Germ cell testicle cancer with mesna and adequate hydration: 1.2 g/m2/day for 5 days, repeat treatment 3 weeks or after recovery from blood toxicity.

How it should be taken : This medication available in the form of injection administered by healthcare providers.

Special Instruction :
*Empty your bladder regularly. Get up at least once during the night to urinate.*It may reduce the number of blood cells that are needed for clotting. To prevent bleeding, avoid situations where bruising or injury may occur.*It may irritate your kidneys and bladder. Drink adequate liquid during the treatment. This precaution is especially important if you have had chemotherapy before.

Side Effects :
CENTRAL NERVOUS SYSTEM:
Confusion, drowsiness, depression, agitation
SKIN:
Hairloss.
GI:
Nausea, vomiting,
MISCELLANEOUS:
Eye inflammation, sore throat, shortness of breath,

Other Precautions :
Monitor kidney functions, urine test, complete blood counts.

Storage Conditions :
Intravenous: Store at 20-25°C.