FLURBIPROFEN

Generic Name : FLURBIPROFEN

TradeName : ARFLUR CR-tab ARFLUR tab BINEA eye drops BRUFEN GEL gel CADIFLUR drops EYEFEN eye drops FBN eye drops FLUBIP eye drops FLUDROP drops FLUFEN drops FLUR eye drops FLURBIREN eye drops FLUROFEN tab FROBEN SR cap LABOFLUR eye drops LORPHEN eye drops OCUFLUR eye drops OPTIFEN eye drops OPTIFLUR eye/ear drops OXIBER eye drops SOFLUR eye/ear drops VISIFLUR drops ZYFLUR eye drops

Why it is prescribed (Indications) : This medication is prescribed for pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), inflammation of eye, dysmenorrhea. It belongs to NSAIDs. It prevents the production of irritant chemicals that causes pain, fever, and inflammation.

When it is not to be taken (Contraindications) : Peptic ulcer, GI bleeding, asthma, treatment of perioperative pain in the setting of coronary artery bypass graft surgery, rhinitis, hypersensitivity; aspirin intolerance; pregnancy (3rd trimester); lactation.

When it is to be taken : Oral: Pain and inflammation associated with musculoskeletal and joint disorders 150-200 mg/day in divided doses, up to 300 mg/day in severe cases. Dysmenorrhoea( pain during menstruation). Initial: 100 mg, then 50-100 mg 4-6 hourly. Max: 300 mg/day. Sore throat Per loz contains 8.75 mg flurbiprofen: 1 loz 3-6 hrly, up to a max of 3 days. Max: 5 loz/day. Eye drops Prophylaxis of miosis during ocular surgery. Adult: As sodium: Instill 1 drop of a 0.03% solution into the eye every 30 minutes starting 2 hr before and ending not < 30 minutes before the surgery.
Ophthalmic Postoperative ocular inflammation Adult: Instill 1 drop of a 0.03% solution into the eye 4 times daily for 1-3 wk starting at 24 hr after surgery.

How it should be taken : It comes as a tablet to take by mouth. It usually is taken two to four times a day. Instill eye drops 30 min before surgery.

Special Instruction :
*Caution should be exercised in patients with kidney or liver, heart diseases, hypertension, NSAID reactions, peptic ulcer, blood clotting problems, pregnant women, breast feeding, elderly patients, and children. *It may cause hypertension; impaired kidney function. *Monitor Complete Blood Count, GI ulceration, Liver function regularly

Side Effects :
GI- Abdominal pain, constipation, diarrhea, dyspepsia/heartburn, flatulence, GI bleeding, nausea, vomiting.
CENTRAL NERVOUS SYSTEM- Memory loss, anxiety, asthenia, depression, dizziness/vertigo, headache, increased reflexes, sleeplessness, uneasiness, nervousness, drowsiness, tremor.
SKIN- Rash.
EYE AND ENT- Stuffy nose, ringing in the ears, vision changes; fibrosis, increased bleeding tendency of ocular tissues in conjunction with eye surgery, constriction of pupil, dilatation of pupil, eye irritation, transient burning and stinging upon instillation (ophthalmic use).
GENITOURINARY- Urinary tract infection.
METABOLIC-NUTRITIONAL- Body weight changes.
MISCELLANEOUS- Edema. Potentially Fatal: Peptic ulceration, bleeding and perforation.

Other Precautions :
Do not take excess dose and avoid prolonged usage.

Storage Conditions :
Ophthalmic: Store at 15-25°C. Oral: Store at 15-25°C. Store it in airtight container and in room temperature.