Mitoxantrone

Generic Name : Mitoxantrone

TradeName : Novantrone

Why it is prescribed (Indications) : Mitoxantrone is an antineoplastic agent which works by interfering with cell reproduction and growth, which helps reduce the number of cancer cells in the body.

When it is not to be taken (Contraindications) : If you are allergic to any ingredient in Mitoxantrone or if you have multiple sclerosis along with certain heart problems

Missed a Dose? :
Contact your consultant for further instructions if you miss an appointment for your mitoxantrone injection.

How it should be taken : • Mitoxantrone is usually given as injection at hospital, or clinic. • If the vial contains particles or is discolored, or cracked or damaged in any way, do not use it.

Special Instruction :
• Mitoxantrone may turn urine a blue-green color. It may also cause the eyes to turn a bluish color which is normal and not a cause for concern. • It also can lower your body's ability to fight infection. • Avoid vaccinations with live vaccines (eg, measles, mumps, oral polio) while you are taking the drug

Side Effects :
Get immediate medical help if you have any of these signs of an allergic reaction like • signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding loss of appetite, mouth sores, unusual weakness; • feeling short of breath, even with mild exertion; • swelling, rapid weight gain; • urinating more or less than usual; • chest pain or tightness, trouble breathing; • black, bloody stools; • skin changes where the medicine
was injected.

Other Precautions :
• It may reduce the platelet counts in your blood. • Patients on Mitoxantrone have developed a type of leukemia. • Mitoxantrone is not recommended for use in CHILDREN because Safety and effectiveness have not been confirmed yet. • Mitoxantrone has been shown to cause damage to the fetus. If you become pregnant while on treatment, discuss with your doctor the benefits and risks of using Mitoxantrone during pregnancy.

Drug Interactions :
There may be other drugs that can interact with Mitoxantrone so kindly consult your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Drugs that cause interaction are • Amphotericin B • Antithyroid agents • Azathioprine • Chloramphenicol • Colchicine or • Flucytosine • Ganciclovir • Interferon • Plicamycin

Storage Conditions :
Store the drug in secure place.