ESOMEPRAZOLE

Generic Name : ESOMEPRAZOLE

TradeName : CESO enteric-coated tab CUCID-ES tab ES-CARE tab ESOCOOL tab ES-OD tab ESOFAG tab ESOFAG-D cap ESOFLO tab ESOMAC tab ESOREST tab ESORIV tab ESOTRAX tab ESOZ inj ESOZ tab ESOZ-D cap ESPRA tab ESTAB tab IGNIS cap IZRA tab IZRA vial IZRA-D cap NEKSIUM TAB tab NEKSIUM vial NEUTRAFLUX film-coated tab NEXPRO FAST tab NEXPRO tab NEXPRO vial NEXPRO-RD 40 cap NEXPRO-RD cap NULOC tab OMIPURE film-coated tab RACIPER SF tab RACIPER tab RACIPER-D cap RACIPER-IV 40 vial SOMPRAZ tab SOMPRAZ vial SOMPRAZ-D cap SOMPRAZ-IT cap ZOSEC-S tab

Why it is prescribed (Indications) : This medication is prescribed for gastroesophageal reflux disease (GERD). With amoxicillin and clarithromycin it is used for treatment of Helicobacter pylori infection and duodenal ulcer. It is also used to aid in reduction in occurrence of gastric ulcers associated with continuous NSAID therapy, and in Zollinger-Ellison syndrome. It blocks the production of acid by the stomach.

When it is not to be taken (Contraindications) : Hypersensitivity along with atazanavir

When it is to be taken : GERD: 20 or 40 mg is given once daily for 4-8 weeks. In children ages 1-11, the dose is 10 or 20 mg daily. H. pylori: 40 mg is administered once daily in combination with amoxicillin and clarithromycin for 10 days. NSAID-induced ulcers is 20 to 40 mg daily for 6 months. Zollinger-Ellison syndrome is treated with 40 mg twice daily.

How it should be taken : It comes as a delayed-release (long-acting) capsule to take by mouth or to open, mix with water, and gives through a feeding tube and as granules to mix with water and take by mouth or give through a feeding tube. It is usually taken once a day at least 1 hour before a meal.

Special Instruction :
*Caution needed for Pediatric, pregnancy, lactation. *It may cause malignancy and liver impairment. *While taking this medication, there is increased risk of developing certain infections such as community-acquired pneumonia.

Side Effects :
CENTRAL NERVOUS SYSTEM- Headache, dizziness, somnolence, aggression, agitation, depression, hallucination.
SKIN- Itching, hair loss, severe allergic reactions, photosensitivity, blistering.
EYE AND ENT- Blurred vision.
GI- Flatulence, abdominal pain, stomach upset, nausea, diarrhea, dry mouth, constipation, GI fungal infection, inflammation of pancreas, mouth ulcer, taste disturbance.
GENITOURINARY- Breast enlargement in men, kidney disorder.
LIVER- Occurrence of confusion, altered level of consciousness and coma as a result of liver failure(Hepatic encephalopathy) , liver failure, inflammation of liver with or without jaundice.
BLOOD- Decrease in white blood cells.
LOCAL- Injection-site reactions including mild local redness and itching with IV administration.
MUSCULOSKELETAL- Muscular weakness, muscle pain.
RESPIRATORY- Asthma, respiratory tract infection.
MISCELLANEOUS- Severe allergic reaction/shock.

Other Precautions :
Take properly as per your doctor's advice.

Storage Conditions :
Injection: Powder for injection: Store at 25°C (77°F). Protect from light. Reconstituted solution for injection should be stored at room temperature up to 30°C and administered within 12 hr after preparation.