DULOXETINE

Generic Name : DULOXETINE

TradeName : 2-DEP tab C-PACT cap DELOK cap DLX tab DULANE cap DULEX cap DULIFE cap DULOCIN tab DULOJOY tab DULOT cap DUMORE cap DUOTOP cap DUPACT cap DUREEP cap DUTIN cap DUVANTA tab DUXET cap DUZAC cap DUZELA cap MYDULA tab NUDEP-20 HG-cap NUDEP-30 HG-cap NUDEP-40 cap SWENTA tab SYLONEX enteric-coated tab SYMBAL tab SYMBAL-M tab SYMPTA tab VERLOX enteric-coated tab

Why it is prescribed (Indications) : It is prescribed for depression, anxiety disorder, and also used for managing pain caused by fibromyalgia and diabetic peripheral neuropathy (DPNP).It maintains the mental balance and stops the movement of pain signals in the brain.

When it is not to be taken (Contraindications) : It may cause uncontrolled narrow-angle glaucoma, liver damage and kidney failure. Harmful in pregnancy and lactation.

When it is to be taken : Depression Adult: Initial Dose: 40 mg per day (administered as 20 mg twice daily) to 60 mg per day (given either once a day or as 30 mg twice daily) without regard to meals.

How it should be taken : It comes as a delayed-release (long-acting) capsule to take by mouth. When duloxetine is used to treat depression, it is usually taken once or twice a day with or without food. (Swallow whole, do not chew/crush.).

Special Instruction :
*Avoid alcohol because alcohol can increase the risk of serious side effects from this medication. *It may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. Get up slowly from bed. *May make you drowsy, dizzy, or may affect your judgment, thinking or coordination. Do not drive a car or operate machinery while taking this medication. *Contact the doctor right away if any signs of suicidal thoughts or actions occur. *Check blood sugar levels closely

Side Effects :
HEART
Hot flush; palpitations; heart attack, hypertensive crisis, abnormal heart rhythm.
CENTRAL NERVOUS SYSTEM
Drowsiness; headache; dizziness; sleeplessness; fatigue; decreased appetite; lack of energy, agitation; tremor; decreased sexual activities, tingling; abnormal dreams, anxiety, migraine, elevated body temperature, sleep disorder; yawning; partial loss of sensitivity, lethargy, vertigo; aggression, anger, restless leg syndrome, seizures upon treatment discontinuation.
SKIN
Abnormally increased perspiration; rash; itching; redness of the skin.
EYE AND ENT
Nasopharynx inflammation; pharynx and larynx pain; blurred vision; sudden eye pressure; perception of sound within the human ear in the absence of corresponding external sound
GI
Nausea; dry mouth; constipation; diarrhea; vomiting; upset stomach; abdominal pain; loose stools; stomach flu; flatulence.
GENITOURINARY
Impotence, frequent daytime urination; ejaculation disorder; abnormal orgasm, delayed ejaculation; urinary tract infection; penis disorder; sexual dysfunction; abnormal uterine bleeding.
HYPERSENSITIVITY
Anaphylactic reaction, rapid swelling (edema) of the dermis, hypersensitivity.
METABOLIC-NUTRITIONAL
Loss of appetite; decreased weight, increased weight; hyperglycemia.
MUSCULOSKELETAL
Muscle cramps, musculoskeletal pain; muscle spasm, muscle pain.
RESPIRATORY
Upper respiratory tract infection; cough.
MISCELLANEOUS
Fever, seasonal allergy; influenza; chill/rigors.

Other Precautions :
Consult your doctor for dosage changes.

Storage Conditions :
Store at 25°C. Store it in air tight container and keep away from children.