CEFAZOLIN

Generic Name : CEFAZOLIN

TradeName : AZOLIN vial CEFADIN vial CEZOLIN IM/IV vial CIPRID vial ORIZOLIN vial OZOLIN inj PREZOLIN vial REFLIN vial SEFAZOL vial

Why it is prescribed
(Indications) : This medication is a cephalosporin antibiotic, prescribed for bacterial infections or preventing bacterial infections before, during, or after certain surgeries. It works by killing sensitive bacteria.

When it is not to be taken
(Contraindications) : Hypersensitivity.

When it is to be taken : IV/IM Susceptible infections 0.5-1 g 6-12 hourly. Max: 6 g/day, up to 12 g/day in severe infections. Surgical prophylaxis 1 g 30-60 minutes pre-op, followed by 0.5-1 g during surgery for lengthy procedures. Continue with 0.5-1 g 6-8 hourly post-op for 24 hour.

How it should be taken
: The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day.

Special Instruction :
*Caution should be exercised in patients with history of liver, kidney, and gastrointestinal diseases.
*It may harmful to kidney function, pregnancy and breast feeding.
*Consider possibility of pseudo membranous colitis in patients who present with diarrhoea after antimicrobial usage.
*Risk of seizures in patients on high doses, especially in kidney failed patients.
*It may decrease prothrombin activity; monitor prothrombin time in patients at risk e.g. those on anticoagulant treatment, prolonged antimicrobial treatment or those with kidney or liver impairment.

Side Effects :
CENTRAL NERVOUS SYSTEM- Hyperactivity.
GI- Abdominal pain; anal itching; loss of appetite, inflammation of colon, diarrhea, nausea, fungal infection of mouth, stomach cramps, vomiting.
GENITOURINARY- Genital itching (including genital fungal infection, vaginal inflammation, vulvar itching).
LIVER- Liver inflammation.
BLOOD- Anemia, bleeding, decrease in white blood cells, platelets.
LAB TESTS- Increased level of liver enzymes, prolonged blood clotting time.
LOCAL- Pain, inflammation of veins.
MUSCULOSKELETAL- Tightness of muscle.
GENITOURINARY- Increased BUN (Blood, urea, Nitrogen) and creatinine, kidney function impairment, toxic nephropathy.
MISCELLANEOUS- Allergy (including anaphylaxis, drug fever, eosinophilia, severe allergic reactions, toxic hives), super infection.

Other Precautions
:
Avoid long-term use, otherwise it will cause secondary infection.
Storage Conditions :
Injection: Store at 25°C.Store in refrigerator. Do not freeze the medication.


No comments:

Post a Comment