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Why it is prescribed (Indications) : It is used to treat high blood pressure. It blocks the action of certain chemicals that tighten the blood vessels, so blood flows more smoothly. This medication is sometimes prescribed for other uses;
When it is not to be taken (Contraindications) : Hypersensitivity. Pregnancy (2nd and 3rd trimester) and lactation
When it is to be taken : Oral Hypertension Adult: Initially, 8 mg once daily adjusted according to response. Maintenance: 8 mg once daily. Max: 32 mg daily. Kidney impairment: For patients with renal impairment or on haemodialysis: Initially, 4 mg once daily. Liver impairment: Initially, 2 mg once daily. Avoid in severe impairment. Oral Heart failure Adult: Initially, 4 mg once daily, may double dose at intervals of not <2 wk. Max: 32 mg daily. kideny impairment: Reduce dose or discontinue treatment if renal function deteriorates. Liver impairment: Initially, 2 mg once daily. Avoid in severe impairment.
How it should be taken : It comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food.
Special Instruction :
1. It may cause a serious allergy. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes throat, or tongue; difficulty swallowing or breathing; or hoarseness. 2. Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider. 3. Monitor serum potassium levels especially in elderly and kidney patients. 4. Hypotension may occur during major surgery and anesthesia due to suppression of the renin-angiotensin system. 5. Caution should be exercised patients with a history of hives, heart, kidney, liver disease or diabetes.
Side Effects :
CENTRAL NERVOUS SYSTEM
Dizziness, headache, vertigo, depression, drowsiness,
METABOLIC
Decreased haemoglobin, kidney impairment.
LIVER
Jaundice
MISCELLANEOUS
Fever, back pain, upper respiratory tract infections, 1st dose orthostatic hypotension, rash.
Other Precautions :
Monitor blood pressure regularly
Storage Conditions :
Oral: Store at 15-30°C.Store it in airtight container and keep away from children.
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